The use of phentermine/topiramate is contraindicated when patients are on a current regimen of isocarboxazid, linezolid, phenelzine, procarbazine, or transdermal selegiline due to the risk of hypertensive episodes.Hepatic impairment: It is important to consider the Child-Pugh score for individuals with hepatic impairment. A Child-Pugh score of 5 or